Cart
sales@molnova.com
m-PEG7-4-nitrophenyl carbonate
CAS No. 678150-56-6
m-PEG7-4-nitrophenyl carbonate( —— )
Catalog No. M24690 CAS No. 678150-56-6
m-PEG7-4-nitrophenyl carbonate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 83 | In Stock |
|
| 5MG | 125 | In Stock |
|
| 10MG | 185 | In Stock |
|
| 25MG | 277 | In Stock |
|
| 50MG | 422 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product Namem-PEG7-4-nitrophenyl carbonate
-
NoteResearch use only, not for human use.
-
Brief Descriptionm-PEG7-4-nitrophenyl carbonate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
-
Descriptionm-PEG7-4-nitrophenyl carbonate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
-
In VitroPROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
-
In Vivo——
-
Synonyms——
-
PathwayPROTACs
-
TargetPROTAC
-
RecptorPEGs|Alkyl/ether
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number678150-56-6
-
Formula Weight461.46
-
Molecular FormulaC20H31NO11
-
Purity>98% (HPLC)
-
SolubilityDMSO:10 mM
-
SMILESCOCCOCCOCCOCCOCCOCCOC(OC1=CC=C([N+]([O-])=O)C=C1)=O
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
molnova catalog
related products
-
(S,R,S)-AHPC-PEG3-N3
(S,R,S)-AHPC-PEG3-N3 is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 3-unit PEG linker used in PROTAC technology. (S,R,S)-AHPC-PEG3-N3 is extracted from patent WO/2016/146985A1.
-
Rpn13 degrader WL40
Rpn13 degrader WL40 (WL40) is a novel covalent ubiquitin receptor Rpn13 degrader by linking the Rpn13 covalent inhibitor RA190 with the cereblon (CRBN) binding ligand thalidomide.
-
ARV-771
ARV-771, a small-molecule pan-BET degrader based on proteolysis-targeting chimera (PROTAC) technology, demonstrates dramatically improved efficacy in cellular models of CRPC as compared with BET inhibition.
